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Cornell University

Van Vliet Group

Laboratory for Material Chemomechanics

Cartoon scientific figure demonstrating the main focus of our research. Figure that showcases a cell and how it interacts with its material environment.

Chemomechanics at the cell-material interface

We explore the mechanisms by which the mechanical and biochemical properties of extracellular microenvironments modulate biological processes. We seek to leverage these mechanisms to improve upon cell therapy manufacturing.

Chemomechanics of complex gels

We explore chemomechanics in synthetic gels that either interface with biological cells, and thus serve as a tool to modulate cell environments; or are not intended as biomaterials, but serve as excellent physical models of such complex biopolymers.

Our Latest Discovery

A Novel Microcarrier-microbioreactor Platform May Improve Manufacture of Mesenchymal Stromal Cell Therapies

Krupczak et al. “Manufacturing mesenchymal stromal cells in a microcarrier-microbioreactor platform can enhance cell yield and quality attributes: case study for acute respiratory distress syndrome.” Journal of Translational Medicine (2024)

Join Us

 

Admitted students who are interested in joining the group should reach out 
to Prof. Krystyn Van Vliet.

Group Meeting

Guests and prospective candidates are welcome to attend our weekly Group Meetings. In these meetings, lab members present on various topics related to research projects currently underway in the lab. We are also happy to invite guest speakers to attend and present to the group. Group Meeting takes place via Zoom each Wednesday from 5:00pm-6:30pm.

If you are interested in attending a Group Meeting, please contact Principal Investigator Krystyn Van Vliet and lab manager Julia Dias to obtain meeting information.

This Month’s Group Meeting Calendar

DateDayTalk TitleSpeaker
February 5Wednesday​​​Enhancing Cell Therapy for Treatment of Acute Respiratory Distress SyndromeBrandon Krupczak
February 12 WednesdayTo Project Proposal: MSC-based Cell Therapy for Multiple Sclerosis (MS)Junsung (John) Lee
February 19WednesdayTo be announcedAnna Jagielska
February 26WednesdayN/AN/A
 
 

 

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